Professor Peter Scammells

Position

Professor of Medicinal Chemistry and Head of the Department of Medicinal Chemistry, Monash University.

Qualifications
•    School of Biological and Chemical Sciences at Deakin University staff position.
•    Alexander von Humboldtfellowship in the Institut für Organische Chemie at the Technische Universtät Darmstadt.
•    Postdoctoral studies in the College of Medicine, University of South Florida with Professor Ray Olsson.
•    PhD (1991) Griffith University with Professor Ronald Quinn.

Expertise
•    Medicinal Chemistry of adenosine and opiate receptors,
•    Application for ionic liquids in pharmaceutical synthesis.

Key Areas of Research

•    The design and synthesis of dual-acting antioxidants.
•    The investigation of radical N-demethylation reactions for the synthesis of pharmaceutical and peripherally selective opiates.
•    The development of adenosine agonists as potential antiarrhythmic agents.
•    The design and synthesis of adenosine allosteric enhancers as potential cardioprotective or neuroprotective agents.
•    The development of irreversible, bifunctional and polyvalent ligands for the study of drug receptor interactions.
•    Applications of ionic liquids in pharmaceutical synthesis.

Selected Publications

Ashton, TD; Scammells, PJ. Microwave Assisted Direct Amination: Rapid Access to Multi-Functionalised N6-Substituted Adenosines. Aust. J. Chem. 2008, 61, 49-58.

Butcher, A; Gregg, A; Scammells, PJ; Rose’Meyer RB. The Effect of a Novel Partial Adenosine A1 Receptor Agonist VCP102 in Reducing Ischemic Damage in the Mouse Heart. Drug Dev. Res. 2008, 68, 529-537.