Dr Jason Smith

  • Jason.Smith@utas.edu.au
  • University of Tasmania

  • Position

    Senior Lecturer at the School of Chemistry, the University of Tasmania.

    Qualifications
    •    Post-doctoral research at The Texas A&M University with Professor Sir Derek H.R. Barton and at The Australian National University with Professor Martin G. Banwell.
    •    PhD, Flinders University, South Australia working with Professor Rolf Prager.

    Expertise
    •    Development of new synthetic methodologies and their application to the synthesis of biologically active and/or structurally complex molecules.
    •    Determination of the reaction mechanism of the oxidation of hydrazides.

    Key Areas of Research

    •    Understanding the mechanism of hydrazide oxidation in the activation of the tuberculosis drug isoniazid.
    •    Design and synthesis of new inhibitors of Mycobacterim tuberculosis.
    •    The design and fabrication of polymer monolith supported catalyst microreactors for organic synthesis.
    •    The use of pyrrole as a template in the synthesis of alkaloids.
    •    Synthesis of phytotoxins from the soil borne bacterium Streptomyces scabies.

    Selected Publications

    Amos, RIJ; Gourlay, BS; Schiesser, CH; Smith, JA; Yates, BF. A Mechanism on the Oxidation of Hydrazides: Application to the Tuberculosis Drug Isoniazid. Chem. Commun., 2008, 1695–1697.