Associate Professor James Ziogas

Position
Associate Professor in the Department of Pharmacology, the University of Melbourne.

Qualifications
•    Postdoctoral studies (1986–1988) the University of Melbourne on a National Heart Foundation Grant, and (1988-1991) Oxford University on a NH&MRC C.J. Martin Overseas Travelling Fellowship working with Dr Tom Cunnane.
•    PhD (1986) the University of Melbourne.

Expertise
•    Regulation of blood pressure, particularly the interaction of the renin-angiotensin system with the sympathetic nervous system.

Key Areas of Research

•    Testing and development of dual action drugs that can block angiotensin AT1 receptors and have antioxidant activity.
•    Novel membrane signalling mechanisms of oestradiol.
•    Regulation of transient receptor potential ion activity.

Selected Publications

Grange, RL; Ziogas, J; North, AJ; Angus, JA; Schiesser, CH. Selenosartans: Novel selenophene analogues of milfasartan and eprosartan. Bioorganic & Medicinal Chemistry Letters, 2008, 18(3): 1241-1244.

Grange RL; Ziogas, J; Angus, JA; Schiesser, CH. Selenofonsartan analogues: novel selenium-containing antihypertensive compounds. Tetrahedron Letters, 2007, 48 (36): 6301-6303.