Professor Steve Bottle

Position

Professor of Chemistry and Director of Research in the School of Physical and Chemical Sciences at the Queensland University of Technology.

Qualifications
•    Postdoctoral studies (1990–1991) Wuerzburg University in Germany as an Alexander von Humboldt Fellow working with Professor Waldemar Adam.
•    PhD (1989) Griffith University working with Professors Ian Jenkins and Ken Busfield and in association with Ezio Rizzardo from the CSIRO.
•    Fellow of the Royal Australian Chemical Institute and between 2002-2007 served on the Board of Directors.

Expertise
•    Free radical chemistry ranging from biological antioxidants to polymer formation and degradation.
•    Development of new medicinal compounds and pharmaceuticals.

Key Areas of Research

•    Design, synthesis and evaluation of novel antioxidant nitroxides.
•    Detecting and controlling degradation in modern materials.
•    Using fluorescence to monitor oxidative stress in cells using Flow
•    Cytometry and Confocal Microscopy.
•    Novel, dual-acting, cardioprotective agents.
•    Monitoring levels of free radicals from particulate pollution including cigarette smoke and vehicle emissions.
•    The use of novel antioxidants to limit oxidative stress in Friedrich’s Ataxia and Ataxia Telangiectasia.
•    Design and synthesis of new profluorescent additives for materials protection and lifetime prediction.

Selected Publications

Bottle, SE; Yan, GP; Peng, L; Jian, SQ; Li, L. Spin probes for electron paramagnetic resonance imaging. Chinese Science Bulletin, 2008, 53(24), 3777-3789.

Bottle, SE; Blinco, JP; Keddie, DJ; Wade, T; Barker, PJ; George, GA. Profluorescent nitroxides: Sensors and stabilizers of radicalmediated oxidative damage. Polymer Degradation and Stability, 2008, 93(9), 1613-1618.